Maryland State Police (MSP) are investigating a fatal multi-vehicle crash that occurred in Frederick County on Sunday.

Troopers responded to the crash at 4:10 p.m. on May 25 near Exit 62 on I-70 in New Market, Maryland.

“The preliminary investigation indicates the driver of a BMW SUV, traveling westbound on I-70 prior to Route 75, rear-ended a box truck. The box truck subsequently traveled across the center median and struck a tractor trailer. The tractor trailer was traveling eastbound on I-70,” MSP said in a news release.

The box truck and tractor trailer both veered off the interstate towards a wooded area adjacent to eastbound I-70 and caught fire.

Two passengers in the box truck were pronounced dead at the scene.

The drivers of the box truck and tractor trailer were airlifted from the scene for medical treatment.

The BMW driver refused medical treatment. Two passengers in the BMW were taken by ambulance to a hospital for treatment.

“Due to the severity of the crash and injuries, the Maryland State Police Crash Team responded to conduct the investigation. The cause and contributing factors involved in this crash remain under investigation.  All possible causes are being considered. The investigation is continuing,” troopers stated.

The crash was caught on Maryland Department of Transportation traffic cameras.